Epidemiological study of intracranial meningiomas in a tertiary care hospital

Abstract

Meningiomas are tumours that arise from the meningothelial cells. Most of these tumours are intracranial; some are intraspinal and few extra cranial. There are many histological variants classified into three grades depending on clinical behaviour. Classification is important for determining the modality of treatment. Objectives: To study the incidence, location, sex and age predilection, histological variants and grading of meningiomas based on WHO 2007 classification and recurrence if present. Materials and methods: All 200 cases of meningiomas. Based on Histological features, typing and grading of meningiomas was done as per the WHO 2007 classification of Meningiomas. Age, Sex incidence, Location of meningiomas were studied. Results: Meningiomas comprised 26.17% of all CNS tumours during the study period. Of 764 CNS tumours, 200 were meningiomas. Most of them were intracranial, predominantly involving the convexities of brain, females and the 41 – 50 age group. Of these, 180 were benign grade I tumours, 12 were grade II and 8 were grade III. The most common histological variant was fibroblastic and meningothelial. Grade II and Grade III tumours commonly recurred. Conclusion: Meningiomas are slow-growing tumours arising from the meningothelial cells accounting for 26.17% of all CNS neoplasms showing a variety of histological patterns, more common in women, predominantly Grade I tumours. Recurrence of tumours depends on histological grade and extent of surgery.