Primary central nervous system sarcomas: clinical, radiological and pathological features in our institution


Wael k. Zakaria, Ahmed N. Taha, Mohamed State


Neurosurgery Department; Mansoura University, EGYPT


ABSTRACT: TObjective: Primary CNS sarcomas are very rare tumors with no defined standard of care. Patients and methods: This study was a retrospective review of seven patients diagnosed with a primary CNS sarcoma at neurosurgery department, Mansoura university hospital between 2006 and 2018. We reviewed the clinical, radiological, and pathological data of these patients. There were 2 female (28.6%) and 5 male (71.4%) with age ranged from 8 years to 73 years (mean age 25.4 years). Three patients (42.9%) had an intracranial sarcoma, and four (57.1%) had intraspinal tumors. All intracranial tumors located in supratentorial region. Results: we have characteristic imaging findings inform of osteolytic bony erosion in 3 patients and marked enhancement of the tumor in 5 (71.4%) patients. We operated upon all patients to remove the tumor surgically with our aim is gross tumor resection. Tumor wae totally resected in 5 patients (71.4%) and subtotal in another 2 patients (28.6%). Tumor has dural attachment in 5 cases (71.4%) and brain invasion was present in all intracranial 3 patients (42.9%). Postoperative radiotherapy was used in 5 patients and postoperative chemotherapy was used in all patients. We used immunohistochemical studies for all patients with the most consistent finding being strong Desmin positivity. The mean length of patients survival was 4.6 years (range from 3 month to 8 years). Conclusions: Primary CNS sarcomas are very rare CNS tumors, total surgical resection and post-operative radio and chemotherapy provided encouraging outcomes.

Keywords: Primary CNS, Sarcoma


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Learning curve in rat dissection for experimental sciatic nerve repair


Marin Andrei (1), Marin Georgiana Gabriela (2), Dobrete Nicoleta Amalia (3), Enescu Dan Mircea (4)


1. Plastic Surgery Department, “Bagdasar Arseni” Emergency Hospital, Bucharest, ROMANIA
2. Cardiology Department, “CC Iliescu” Hospital, Bucharest, ROMANIA
3. Haematology Department, “Fundeni” Hospital, Bucharest, ROMANIA
4. Plastic Surgery Department, “Grigore Alexandrescu” Emergency Paediatric Hospital, Bucharest, ROMANIA


ABSTRACT: The baseline for any key research in nerve regeneration is an experimental model and the sciatic nerve in the rat model is the workhorse in this field. Although physically resistant to external traumas, a surgical intervention constitutes a major distress even for a rat. In the following presentation, we will analyse the learning curves for different stages in the rat sciatic nerve surgery as well as possible factors which influence these times.

Keywords: learning curve, operation times, sciatic nerve rat, nerve defect


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Syringobulbia and syringomyelia in a case with Chiari 0 malformation successfully treated by posterior fossa reconstruction. Case presentation and literature review


R.B. Sandu (1), M.I. Pantiru (1), M. Cosman (2), I. Poeata (1,2)

1. “Prof Dr. N.Oblu” Clinic Emergency Hospital, Iasi, ROMANIA
2. "Grigore T. Popa” University of Medicine and Pharmacy, Iasi, ROMANIA


ABSTRACT: “Chiari zero malformation” is a rare and a relatively new described condition which associates syringohydromyelia without caudal displacement of the cerebellar tonsils through the foramen magnum. We present a case of a 40 years old woman with Chiari zero malformation with both syringomyelia and syringobulbia and a good clinical and radiological outcome after posterior fossa decompression. The presence of associated syringomyelia and syringobulbia in this condition is less frequent and it usually occurs in younger patients. In our case we considered syringobulbia as being an extension of syringomyelia.

Keywords: Chiari zero malformation, syryngomyelia, syringobulbia, cerebellar tonsils


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Quality and reliability of information available on YouTube videos pertaining to transforaminal lumbar epidural steroid injections


Aysel Gürcan Atci (1), Ibrahim Burak Atci (2)

1. MD. Specialist. Baltalimanı Bone and Joint Research and Education Hospital, Department of Physical Therapy Rehabilitation, TURKEY
2. MD. Assoc. Prof. Istanbul Training and Research Hospital, Department of Neurosurgery, TURKEY


ABSTRACT: Background. This study analyses the transforaminal lumbar steroid injection videos that have the highest views and likes on YouTube, and attempts to reveal the video qualities in order to contribute to the literature. Methods. For review, “transforaminal lumbar steroid injection” was written to the standard YouTube search bar, and the videos with the highest views were ranked using advanced search preferences. The 50 most widely viewed videos were watched and scored by 2 physicians. Results. The mean Modified DISCERN Score of the videos was 2,66+/-1,032 (the lowest: 1; the highest: 4) while the mean GQS score was 2,876+/-1,06 (the lowest: 1; the highest:4). In addition, the mean DISCERN score and the mean GQS value were 3,51 and 3,82, respectively, for the informational videos that were uploaded by health professionals but did not contain actual surgery. Conclusion. We think that medical associations and state authorities in medicine should check the validity and accuracy of the information on the internet and should support the society in access to the most correct information.

Keywords: YouTube, videos, transforaminal lumbar epidural steroid injections, discern, global quality index


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