talk and die syndrome
traumatic brain injury
neurocritical care
narrative review

How to Cite

Lozada-Martínez, I. ., Galeano-Buelvas, A. ., Pearson-Arrieta, A. ., Diaz-Castillo, O. ., Ortega-Sierra, M. ., Robledo-Arias, J. ., Serna-Trejos, J. S. ., Mantilla-Pardo, J. C. ., Betancourt-Cundar, D., Frias-Bechara, R. E. ., Mendez-Martinez, H. Y. ., & Moscote-Salazar, L. R. . (2021). Talk and Die Syndrome: A comprehensive review. Romanian Neurosurgery, 35(3), 262–269. Retrieved from https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/2063


The "Talk and Die" Syndrome is described as the clinical deterioration following a mild to moderate traumatic brain injury. In the face of this event, individuals are able to articulate recognizable words and then deteriorate within 48 hours of the injury. This syndrome represents a major public health challenge due to its high morbidity and mortality rate; it develops from an intracranial haemorrhage causing an increase in intracranial pressure and leading the person to a neurological crisis with focal signs, coma and later death.



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