Association of platelet count and platelet indices with cranial meningioma

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Yasar Karatas
Fatih Keskin
Mehmet Fatih Erdi
Bulent Kaya
Densel Arac
Emir Kaan Izci
Erdal Kalkan

Abstract

Introduction and Objectives: In this study, we aimed to investigate whether platelet count (PLT) and platelet indices included mean platelet volume (MPV), platecrit (PCT), platelet distribution width  (PDW) values can be used as diagnostic markers in cranial meningiomas.


Materials and Methods: The study included results of 29 patient and 47 healthy contributors. Based on pathologies, the patients were divided into two groups. The first group included meningioma patients and the second one included healthy individuals. Healthy contributors named control group. Platelet count and platelet indices were determined using Sysmex XN 550 haematology analyzer. The preoperative platelet count (PLT) and platelet indices included mean platelet volume (MPV), platecrit (PCT), platelet distribution width  (PDW) values were recorded from the routine laboratory tests.


Results: There was no statistically significant difference in PLT between the meningioma and healthy groups (p = 0.217). There was a statistically significant difference in PCT between the meningioma group and the healthy group (p = 0.002). There was a statistically significant difference in PDW between meningioma group and healthy group (p = 0.001). In terms of MPV, there was a statistically significant difference between meningioma group and the healthy group (p = 0.001)


Conclusion: Platelet count and indices are easily available in the routine blood tests. Despite the retrospective design and small sample size, our findings suggest that altered MPV, PDW and PCT levels might serve as potential biomarkers for the diagnosis of meningiomas.

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How to Cite
Karatas, Y., Keskin, F., Erdi, M., Kaya, B., Arac, D., Izci, E., & Kalkan, E. (2020). Association of platelet count and platelet indices with cranial meningioma. Romanian Neurosurgery, 34(1), 117-120. Retrieved from https://www.journals.lapub.co.uk/index.php/roneurosurgery/article/view/1351
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Author Biographies

Yasar Karatas

Medova Hospital, Department of Neurosurgery, Konya, Turkey

Fatih Keskin

Necmettin Erbakan University, Meram Medical Faculty, Department of Neurosurgery, Konya, Turkey

Mehmet Fatih Erdi

Necmettin Erbakan University, Meram Medical Faculty, Department of Neurosurgery, Konya, Turkey

Bulent Kaya

Medova Hospital, Department of Neurosurgery, Konya, Turkey

Densel Arac

Necmettin Erbakan University, Meram Medical Faculty, Department of Neurosurgery, Konya, Turkey

Emir Kaan Izci

Meram Training and Research Hospital, Department of Neurosurgery, Turkey

Erdal Kalkan

Medova Hospital, Department of Neurosurgery, Konya, Turkey