Risk factors for preoperative and postoperative late seizure in supratentorial meningiomas A retrospective analysis of 63 patients

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Rahsan Kemerdere
Mehmet Yigit Akgun
Orkhan Alizada
Sureyya Toklu
Burak Tahmazoglu
Taner Tanriverdi

Abstract

Introduction. Seizure following meningioma surgery is common and management may be challenging. Identifying risk factors may help physicians to initiate optimal medical management. The aim of this study is to report seizure outcome and risk factors for perioperative seizure.


Materials and Methods. Sixty-three adult patients who underwent supratentorial meningioma resection were included, and perioperative data and long-term follow-up were provided in this retrospective study. Binary logistic regression analysis was used to identify the risk factors for perioperative seizure and postoperative late seizure.


Results. The results showed that 20 (37.1 %) patients had preoperative seizure and 10 (50 %) patients were seizure free at the long-term follow-up. Absence of headache was associated with preoperative seizure (p=0.002) while presence of early seizure was significant predictor for postoperative late seizure (p=0.03). Although not significant, occurrence of surgical complications (p=0.08) and non-skull base location (p=0.06) tended toward being a significant risk factor for postoperative late seizure.


Conclusion. Presence of early seizures, surgical complications and locations out of skull base may direct postoperative anti-epileptic treatment to decrease seizure incidence which, indeed, increases quality of life for patients with meningioma.

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How to Cite
Kemerdere, R., Akgun, M., Alizada, O., Toklu, S., Tahmazoglu, B., & Tanriverdi, T. (2019). Risk factors for preoperative and postoperative late seizure in supratentorial meningiomas. Romanian Neurosurgery, 33(3), 316-321. https://doi.org/10.33962/roneuro-2019-053
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Author Biographies

Rahsan Kemerdere

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY

Mehmet Yigit Akgun

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY

Orkhan Alizada

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY

Sureyya Toklu

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY

Burak Tahmazoglu

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY

Taner Tanriverdi

Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, TURKEY