Anatomical localization of intracranial grade II meningiomas in North-Eastern Romania Our 25-years experience

Main Article Content

A. I. Cucu
Claudia Florida Costea
Mihaela Dana Turliuc
Cristina Mihaela Ghiciuc
B. Costachescu
Roxana Popescu
Gabriela Florenta Dumitrescu
Anca Sava
Daniela Maria Tanase
R. Arbore-Sorete
I. Poeata

Abstract

Objective. Our research aims to assess a possible connection between tumour localization and histological subtypes of grade II meningiomas.


Material and methods. 143 patients with grade II WHO meningiomas underwent surgical resection in "Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași between 1990 and 2015. The collected data included: patient age, gender, tumour localization and histopathological diagnosis (atypical, clear cells and chordoid meningioma).


Results. 135 (94.4%) of all 143 patients with grade II meningiomas were atypical meningiomas, 6 (4.2%) were cell clear meningiomas and only 2 (1.4%) were chordoid meningiomas. As concerns their distribution by gender, 79 (55.2%) were female and 64 (44.8%) were male. Grade II meningiomas were most commonly located at convexity 49.7% (n=71), followed by skull base in 30.8% (n=44) of the cases and parasagittal/falcine in 14.7% (n=21) of the patients.


Conclusions. The most common localization of grade II meningiomas was convexity, followed by skull base, parasagittal/falcine and intraventricular areas. We have also noticed that convexity meningiomas are more frequent in women, unlike the other anatomical localizations in which the male-female ratio is almost equal. Therefore, further research is necessary to determine the role of embryological, anatomopathological and genetic factors in underlying the connection between meningioma grade and anatomical localization.

Article Details

How to Cite
Cucu, A., Costea, C., Turliuc, M., Ghiciuc, C., Costachescu, B., Popescu, R., Dumitrescu, G., Sava, A., Tanase, D., Arbore-Sorete, R., & Poeata, I. (2019). Anatomical localization of intracranial grade II meningiomas in North-Eastern Romania. Romanian Neurosurgery, 33(3), 232-238. https://doi.org/10.33962/roneuro-2019-039
Section
Articles
Author Biographies

A. I. Cucu

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

Claudia Florida Costea

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

Mihaela Dana Turliuc

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

Cristina Mihaela Ghiciuc

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

B. Costachescu

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

Roxana Popescu

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

Gabriela Florenta Dumitrescu

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

Anca Sava

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

Daniela Maria Tanase

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA

R. Arbore-Sorete

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

I. Poeata

"Prof. Dr. N. Oblu" Emergency Clinical Hospital Iași, ROMANIA

"Grigore T. Popa" University of Medicine and Pharmacy Iași, ROMANIA